By Terry F. Davies
During this thought-provoking booklet, unusual clinicians offer stimulating guideline and insights right into a wide selection of endocrine matters, instructing readers sleek administration of the stipulations defined and providing specified access into the literature. The textual content displays a lot of the curriculum for scientific endocrine education advised by means of the organization of application administrators in medical Endocrinology. Concise situations are via a number of selection inquiries to improve studying.
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Extra info for A Case-Based Guide to Clinical Endocrinology (Contemporary Endocrinology)
The effect of the menopause on prolactin levels in patients with hyperprolactinaemia. Clin Endocrinol (Oxf) 2001;54:295–300. Questions 1. Microprolactinomas are the most frequent pituitary tumors. True or false? 2. They invariably cause amenorrhea and galactorrhea in women. True or false? 3. The best treatment of microprolactinomas is A. Medical with dopamine agonists B. Surgical C. Both 4. Withdrawal from dopamine-agonist is invariably followed by recurrent hyperprolactinemia. True or false? Chapter 3 Cushing’s Disease Kawaljeet Kaur and James W.
All three of these tests are complementary, but each has limitations. Traditionally, the 24-hour urine free cortisol was considered the gold standard; as our case illustrates, many patients with Cushing’s do not have elevations of urine free cortisol and the sensitivity of this test is only 45% to 71% at a specificity of 100%. Multiple urine collections are often needed when the degree of hypercortisolism is mild, and the cumbersome nature of this test makes it less than ideal for repeat testing.
She was not cushingoid (Fig. 1). Her skin did not show significant thinning, acanthosis, or striae. There was some facial rounding but no significant supraclavicular fullness. The physical exam was otherwise unremarkable. 0), and lumbar spine was normal. Family history was negative for any pituitary, adrenal, thyroid diseases, or osteoporosis. Because of the weight gain, hypertension, and low bone density with fractures, endogenous hypercortisolism (Cushing’s syndrome) was considered. 3). A 24-hour urine cortisol was 40 g (normal is less than 45 g/24 hours).